Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380233 | 0.94 | F10 (0.51) | F10 | |
| SCHEMBL8315691 | 0.88 | F10 (0.54) | F10NPC1TP53TSHRRAB9A | |
| SCHEMBL5873331 | 0.88 | F10 (0.55) | F10NPC1TP53TSHRRAB9A | |
| SCHEMBL1378537 | 0.86 | F10 (0.53) | F10 | |
| SCHEMBL1376974 | 0.86 | F10 (0.56) | F10TP53 | |
| SCHEMBL1377268 | 0.85 | F10 (0.55) | F10TSHR | |
| SCHEMBL1379231 | 0.84 | F10 (0.54) | F10 | |
| SCHEMBL1377046 | 0.83 | F10 (0.60) | F10 | |
| SCHEMBL1380185 | 0.83 | F10 (0.52) | F10 | |
| SCHEMBL1379885 | 0.83 | F10 (0.56) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| JP-2006512321-A | — | — | 2006-04-13 | — | — | JP | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | disclosed |