Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315691 | 0.92 | F10 (0.54) | F10TP53RAB9ANPC1TSHR | |
| SCHEMBL1378537 | 0.90 | F10 (0.53) | F10 | |
| SCHEMBL1376974 | 0.89 | F10 (0.56) | F10TP53 | |
| SCHEMBL1377046 | 0.89 | F10 (0.60) | F10 | |
| SCHEMBL1376448 | 0.88 | RAB9A (0.52) | F10TP53RAB9ANPC1TSHR | |
| SCHEMBL1377268 | 0.88 | F10 (0.55) | F10TSHR | |
| SCHEMBL1376606 | 0.88 | F10 (0.59) | F10 | |
| SCHEMBL1380945 | 0.88 | F10 (0.50) | F10TP53RAB9ANPC1TSHR | |
| SCHEMBL1379231 | 0.87 | F10 (0.54) | F10 | |
| SCHEMBL6214739 | 0.87 | F10 (0.57) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006519188-A | — | — | 2006-08-24 | — | — | JP | claimed |
| EP-1597244-A1 | ETHYNYL DERIVATIVES SERVING AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2005-11-23 | — | — | EP | claimed |
| EP-1549304-A1 | HETEROCYCLIC AMIDES AND THEIR USE IN TREATING THROMBOEMBOLIC DISEASES AND TUMORS | MERCK PATENT GmbH (DE) | 2005-07-06 | — | — | EP | claimed |
| WO-2004076429-A1 | ETHYNYL DERIVATIVES SERVING AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2004-09-10 | — | — | WO | claimed |
| WO-2004035039-A1 | HETEROCYCLIC AMIDES AND THEIR USE IN TREATING THROMBOEMBOLIC DISEASES AND TUMORS | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | WO | claimed |