Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15353819 | 0.93 | KCNJ1 (0.32) | KCNJ1KDM4ELMNATSHRHTT | |
| SCHEMBL15353817 | 0.93 | KCNJ1 (0.32) | KCNJ1KDM4ELMNATSHRHTT | |
| SCHEMBL15353818 | 0.93 | KCNJ1 (0.32) | KCNJ1KDM4ELMNATSHRHTT | |
| SCHEMBL1119765 | 0.91 | CCR2 (0.39) | — | |
| SCHEMBL13809459 | 0.84 | CCR2 (0.34) | KCNJ1TSHRALDH1A1KMT2A | |
| SCHEMBL1120068 | 0.84 | CCR2 (0.39) | — | |
| SCHEMBL13011668 | 0.84 | CCR2 (0.39) | — | |
| SCHEMBL13011667 | 0.84 | CCR2 (0.39) | — | |
| SCHEMBL1119752 | 0.84 | CYP3A4 (0.35) | KCNJ1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL13043838 | 0.83 | CCR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076512-A1 | CARBOXAMIDΞ COMPOUNDS AND THEIR USE AS CHEMOKINE RECEPTOR AGONISTS | EPIX DELAWARE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |