SCHEMBL13809573

SCHEMBL13809573

CN1c2ccccc2C(C)(C)C12C=Nc1c(ccc3c4c(ccc13)OC1(C=N4)N(C)c3ccccc3C1(C)C)O2

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.82
KDM4E B2RXH2 7/20 0.82
THRB P10828 5/20 0.82
SMN1; SMN2 Q16637 4/20 0.82
L3MBTL1 Q9Y468 3/20 0.82
ALOX12 P18054 2/20 0.82
PKM P14618 2/20 0.82
LMNA P02545 5/20 0.71
ALDH1A1 P00352 5/20 0.71
GAA P10253 5/20 0.71
RECQL P46063 3/20 0.71
TDP1 Q9NUW8 3/20 0.71
HPGD P15428 2/20 0.71
HTT P42858 2/20 0.71
MAPK1 P28482 2/20 0.71
POLB P06746 1/20 0.71
NPSR1 Q6W5P4 3/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2C9 P11712 1/20 0.66
CYP2C19 P33261 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13809421 0.92 MAPT (0.89) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL13839771 0.90 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL29493002 0.90 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL80364 0.90 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL3166534 0.90 MAPT (0.68) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL13809657 0.89 MAPT (0.81) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL12125222 0.87 MAPT (0.67) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL4981297 0.87 MAPT (0.65) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL8504276 0.87 MAPT (0.81) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1
SCHEMBL12415230 0.87 MAPT (0.70) MAPTKDM4ETHRBSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754614-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2009-06-17 EP disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed