SCHEMBL13809657

SCHEMBL13809657

CN1c2ccccc2C(C)(C)C12C=Nc1c(ccc3cc4ccc5c(c4cc13)N=CC1(O5)N(C)c3ccccc3C1(C)C)O2

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.81
KDM4E B2RXH2 7/20 0.81
THRB P10828 5/20 0.81
SMN1; SMN2 Q16637 4/20 0.81
ALOX12 P18054 2/20 0.81
L3MBTL1 Q9Y468 2/20 0.81
PKM P14618 2/20 0.81
LMNA P02545 4/20 0.77
ALDH1A1 P00352 4/20 0.77
GAA P10253 4/20 0.77
RECQL P46063 3/20 0.77
TDP1 Q9NUW8 3/20 0.77
HPGD P15428 2/20 0.77
HTT P42858 2/20 0.77
MAPK1 P28482 2/20 0.77
POLB P06746 1/20 0.77
NPSR1 Q6W5P4 3/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8504276 0.95 MAPT (0.81) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13839771 0.89 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL80364 0.89 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493002 0.89 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13809573 0.89 MAPT (0.82) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL23800880 0.89 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL809230 0.89 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29566059 0.89 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL4620516 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13809421 0.86 MAPT (0.89) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754614-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2009-06-17 EP disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed