Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362738 | 0.86 | MAPT (0.75) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL10028049 | 0.82 | MAPT (0.66) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL21119020 | 0.78 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL14267957 | 0.78 | MAPT (0.64) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL16029701 | 0.77 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3063864 | 0.76 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL21067641 | 0.76 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL10405791 | 0.76 | HSD17B10 (0.72) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL12572953 | 0.75 | HSD17B10 (0.60) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL31358799 | 0.72 | KMT2A (0.66) | MAPTKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078588-A2 | COMPOSITION FOR PREVENTION AND TREATMENT OF CANCER CONTAINING PYRIMIDINE DERIVATIVES INHIBITING ACTIVITY OF PROTEIN PHOSPHATASES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-06-25 | — | — | WO | disclosed |