Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063864 | 0.89 | MAPT (0.65) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL14267957 | 0.88 | MAPT (0.64) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL3362738 | 0.85 | MAPT (0.75) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL14267959 | 0.84 | MAPT (0.60) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL30775594 | 0.79 | ALDH1A1 (0.66) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL2636529 | 0.79 | ALDH1A1 (0.66) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL10028049 | 0.78 | MAPT (0.66) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL2636854 | 0.78 | ALDH1A1 (0.68) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1317292 | 0.76 | KMT2A (0.66) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL13809595 | 0.76 | MAPT (0.63) | MAPTSMN1; SMN2RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |