Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377794 | 0.96 | HTR6 (0.51) | MEN1MAPTKMT2ALMNAGAA | |
| Hydrochloric Acid SCHEMBL27585546 | 0.95 | HTR6 (0.50) | MEN1MAPTKMT2ALMNAGAA | |
| SCHEMBL1380651 | 0.86 | HTR6 (0.60) | HTR6HTR1D | |
| SCHEMBL1380901 | 0.85 | HTR6 (0.55) | HTR6 | |
| Hydrochloric Acid SCHEMBL5550931 | 0.85 | HTR6 (0.59) | LMNAKDM4EHTR6ALDH1A1HTR1D | |
| SCHEMBL1380667 | 0.83 | HTR6 (0.48) | MAPTKMT2AHTR6 | |
| SCHEMBL1381062 | 0.82 | HTR6 (0.47) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL1381741 | 0.82 | SLC22A12 (0.53) | MAPTHTR6HTR1D | |
| SCHEMBL4315177 | 0.82 | HTR6 (0.49) | MAPTHTR6TSHRHTR3EHTR3B | |
| SCHEMBL3609792 | 0.81 | HTR6 (0.66) | MEN1MAPTKMT2AKDM4EHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |