Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.62 |
| ▸ | PGR | P06401 | 10/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075508 | 0.86 | NR3C1 (0.84) | NR3C1NR3C2PGR | |
| SCHEMBL4071511 | 0.81 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL13810896 | 0.81 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL4074372 | 0.81 | NR3C1 (0.88) | NR3C1NR3C2PGR | |
| SCHEMBL3581956 | 0.78 | NR3C1 (0.86) | NR3C1NR3C2PGR | |
| SCHEMBL4069727 | 0.78 | NR3C1 (0.76) | NR3C1NR3C2PGR | |
| SCHEMBL4066301 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL3580755 | 0.76 | NR3C1 (0.86) | NR3C1NR3C2PGR | |
| SCHEMBL4066700 | 0.76 | NR3C1 (0.94) | NR3C1NR3C2PGR | |
| SCHEMBL13810923 | 0.76 | NR3C1 (0.72) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836166-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2009-06-17 | — | — | EP | disclosed |