Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 19/20 | 0.64 |
| ▸ | PGR | P06401 | 13/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074617 | 0.89 | NR3C2 (0.68) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL13810710 | 0.83 | NR3C1 (0.59) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4407316 | 0.83 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL4072559 | 0.83 | NR3C1 (0.78) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4406095 | 0.83 | NR3C1 (0.69) | NR3C1NR3C2PGR | |
| SCHEMBL4407448 | 0.79 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL4069137 | 0.79 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL4071747 | 0.78 | NR3C2 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4065461 | 0.78 | NR3C1 (0.70) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4069539 | 0.78 | NR3C1 (0.63) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836166-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2009-06-17 | — | — | EP | disclosed |