Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810562 | 0.93 | PPARG (0.42) | PPARGPPARDPPARALMNAMAPT | |
| SCHEMBL13810553 | 0.92 | PPARG (0.45) | PPARGPPARDPPARAKDM4ELMNA | |
| SCHEMBL13810572 | 0.92 | KMT2A (0.43) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL4331640 | 0.92 | PPARG (0.42) | PPARGPPARDPPARAKDM4ELMNA | |
| SCHEMBL13810555 | 0.91 | PPARG (0.41) | PPARGPPARAKDM4ELMNACYP2D6 | |
| SCHEMBL4334617 | 0.90 | ALDH1A1 (0.41) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL4328960 | 0.89 | PPARG (0.40) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL13810557 | 0.89 | PPARA (0.50) | PPARGPPARDPPARAMAPT | |
| SCHEMBL4334222 | 0.89 | SMN1; SMN2 (0.48) | PPARGLMNAMAPTCYP2D6CYP2C19 | |
| SCHEMBL4486227 | 0.88 | KDM4E (0.47) | PPARGPPARDPPARAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |