Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794052 | 0.89 | F10 (0.66) | F10DRD4MCHR1SIGMAR1JAK1 | |
| SCHEMBL1379384 | 0.89 | F10 (0.66) | F10DRD4MCHR1SIGMAR1JAK1 | |
| SCHEMBL1652652 | 0.85 | F10 (0.69) | F10DRD4MCHR1KCNH2BRD4 | |
| SCHEMBL3803431 | 0.82 | CCR2 (0.45) | F10 | |
| SCHEMBL1379748 | 0.81 | F10 (0.57) | F10 | |
| SCHEMBL3799822 | 0.79 | F10 (0.62) | F10DRD4MCHR1SIGMAR1JAK1 | |
| SCHEMBL1381476 | 0.79 | F10 (0.62) | F10DRD4MCHR1SIGMAR1JAK1 | |
| SCHEMBL1652651 | 0.79 | F10 (0.69) | F10DRD4MCHR1JAK1JAK3 | |
| SCHEMBL1383134 | 0.78 | F10 (0.63) | F10DRD4MCHR1SIGMAR1BRD4 | |
| SCHEMBL1381696 | 0.78 | F10 (0.63) | F10DRD4MCHR1SIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4658940-B2 | — | — | 2011-03-23 | — | — | JP | claimed |