Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382329 | 0.93 | FOLH1 (0.66) | FOLH1AKR1B1CYP2D6CYP2C9HIF1A | |
| SCHEMBL2707508 | 0.93 | FOLH1 (0.66) | FOLH1AKR1B1CYP2D6CYP2C9HIF1A | |
| SCHEMBL18095084 | 0.91 | FOLH1 (0.63) | FOLH1AKR1B1CYP2D6CYP2C9HIF1A | |
| SCHEMBL371526 | 0.89 | FOLH1 (0.70) | FOLH1CYP2D6CYP2C9HIF1AANPEP | |
| SCHEMBL4402323 | 0.89 | AKR1B1 (0.62) | AKR1B1HIF1A | |
| SCHEMBL30395109 | 0.85 | FOLH1 (0.66) | FOLH1CYP2D6CYP2C9HIF1AANPEP | |
| SCHEMBL1817886 | 0.85 | FOLH1 (0.66) | FOLH1CYP2D6CYP2C9HIF1AANPEP | |
| SCHEMBL27705266 | 0.84 | FOLH1 (0.59) | FOLH1GRM2GRM3CYP2D6CYP2C9 | |
| SCHEMBL70565 | 0.82 | AKR1B1 (0.71) | AKR1B1HIF1A | |
| SCHEMBL27705268 | 0.82 | FOLH1 (0.58) | FOLH1GRM2GRM3CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553809-B2 | Fc receptor modulators and uses thereof | ILEXUS PTY LIMITED (AU) | 2009-06-30 | — | — | US | disclosed |
| US-7553809-B2 | Fc receptor modulators and uses thereof | ILEXUS PTY LIMITED (AU) | 2009-06-30 | — | — | US | disclosed |