Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 11/20 | 0.56 |
| ▸ | FADS1 | O60427 | 2/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812606 | 0.89 | P2RX1 (0.59) | P2RX1FADS1P2RX4P2RX7MAPT | |
| SCHEMBL3863657 | 0.88 | P2RX1 (0.62) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812602 | 0.84 | P2RX1 (0.58) | P2RX1FADS1P2RX4P2RX7MAPT | |
| SCHEMBL13812577 | 0.84 | P2RX1 (0.55) | P2RX1FADS1P2RX4P2RX7MAPT | |
| SCHEMBL13812642 | 0.83 | P2RX1 (0.61) | P2RX1FADS1P2RX4P2RX7MAPT | |
| SCHEMBL13812578 | 0.82 | P2RX1 (0.61) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812562 | 0.82 | TMPRSS4 (0.62) | P2RX1FADS1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812655 | 0.81 | KCNMA1 (0.51) | P2RX1P2RX4P2RX7MAPTMAPK1 | |
| SCHEMBL13812608 | 0.80 | P2RX1 (0.58) | P2RX1FADS1P2RX4P2RX7MAPT | |
| SCHEMBL13812601 | 0.80 | P2RX1 (0.58) | P2RX1FADS1P2RX4P2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |