Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812627 | 0.88 | MEN1 (0.55) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL3861646 | 0.88 | KCNMA1 (0.56) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812701 | 0.85 | KCNMA1 (0.53) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812569 | 0.85 | MEN1 (0.52) | MEN1KMT2ATMPRSS4KCNMA1MAPK1 | |
| SCHEMBL13812704 | 0.85 | MEN1 (0.49) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812598 | 0.83 | KCNMA1 (0.51) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812700 | 0.83 | KCNMA1 (0.58) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812706 | 0.83 | MEN1 (0.52) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812622 | 0.83 | KCNMA1 (0.55) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 | |
| SCHEMBL13812900 | 0.82 | KCNMA1 (0.50) | MEN1KMT2ATMPRSS4KCNMA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |