Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 14/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MYLK | Q15746 | 1/20 | 0.53 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812842 | 0.97 | TMPRSS4 (0.57) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812690 | 0.93 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812831 | 0.90 | TMPRSS4 (0.56) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812711 | 0.86 | TMPRSS4 (0.64) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812830 | 0.85 | TMPRSS4 (0.58) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL4209815 | 0.85 | TMPRSS4 (0.59) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812721 | 0.85 | KCNMA1 (0.48) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812538 | 0.84 | TMPRSS4 (0.64) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL13812821 | 0.84 | TMPRSS4 (0.55) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL4216160 | 0.81 | TMPRSS4 (0.60) | TMPRSS4P2RX1P2RX4P2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |