Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064102 | 0.89 | CALCA (0.58) | CALCAKMT2ARPS6KB1EGLN1SMN1; SMN2 | |
| SCHEMBL6504246 | 0.85 | CALCA (0.60) | CALCAKMT2ARPS6KB1EGLN1SMN1; SMN2 | |
| SCHEMBL6490436 | 0.85 | CALCA (0.62) | CALCAKMT2ARPS6KB1EGLN1SMN1; SMN2 | |
| SCHEMBL4060740 | 0.84 | CALCA (0.61) | CALCAKMT2ARPS6KB1EGLN1SMN1; SMN2 | |
| SCHEMBL4066025 | 0.83 | KMT2A (0.43) | CALCAKMT2ARPS6KB1SMN1; SMN2CTNNB1 | |
| SCHEMBL4059851 | 0.83 | CALCA (0.63) | CALCAKMT2ARPS6KB1EGLN1 | |
| SCHEMBL7101920 | 0.83 | CALCA (0.60) | CALCAKMT2ARPS6KB1EGLN1SMN1; SMN2 | |
| SCHEMBL14447145 | 0.82 | KMT2A (0.42) | CALCAKMT2ARPS6KB1SMN1; SMN2CTNNB1 | |
| SCHEMBL4067905 | 0.82 | KMT2A (0.61) | CALCAKMT2ARPS6KB1EGLN1 | |
| SCHEMBL4067912 | 0.82 | KMT2A (0.61) | CALCAKMT2ARPS6KB1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796267-B2 | Oxazolidinone derivatives and methods of use | CONCERT PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| EP-1664046-B1 | AZA-QUINOLINOL PHOSPHONATE INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2009-06-17 | — | — | EP | disclosed |