Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812977 | 0.83 | GABBR2 (0.51) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL29991645 | 0.82 | KMT2A (0.50) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL4065318 | 0.82 | KMT2A (0.50) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL27225170 | 0.81 | KMT2A (0.49) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL22184593 | 0.79 | KMT2A (0.51) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL574174 | 0.79 | KMT2A (0.51) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL24496115 | 0.78 | KMT2A (0.47) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL22184570 | 0.78 | KMT2A (0.47) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL6944883 | 0.78 | KMT2A (0.47) | KMT2AGABBR2GABBR1CYP1A2MEN1 | |
| SCHEMBL4712427 | 0.78 | KMT2A (0.50) | KMT2AGABBR2GABBR1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590341-B1 | 2-AMINOPYRIDINE SUBSTITUTED HETEROCYCLES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER LAMBERT CO (US) | 2009-06-17 | — | — | EP | disclosed |