Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.37 |
| ▸ | GLP1R | P43220 | 8/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14750406 | 0.92 | SMN1; SMN2 (0.39) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL26032226 | 0.91 | HPGD (0.43) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL25100591 | 0.91 | SMN1; SMN2 (0.51) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL25875583 | 0.89 | HPGD (0.46) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL21648778 | 0.89 | CYP2C19 (0.36) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL25875243 | 0.88 | SMN1; SMN2 (0.47) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL23760365 | 0.88 | SMN1; SMN2 (0.47) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL27306806 | 0.86 | SMN1; SMN2 (0.37) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL16118174 | 0.85 | SMN1; SMN2 (0.38) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL26032028 | 0.85 | HPGD (0.40) | HPGDHTTSMN1; SMN2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553816-B2 | p-amidobenzylethers in drug delivery agents | SEATTLE GENETICS, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-7553816-B2 | p-amidobenzylethers in drug delivery agents | SEATTLE GENETICS, INC. (US) | 2009-06-30 | — | — | US | disclosed |