Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GLP1R | P43220 | 8/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13814445 | 0.89 | HPGD (0.48) | HPGDSMN1; SMN2HTTGLP1RHDAC3 | |
| SCHEMBL25100591 | 0.88 | SMN1; SMN2 (0.51) | HPGDSMN1; SMN2HTTHDAC3HDAC4 | |
| SCHEMBL23680206 | 0.87 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2HTTHDAC3HDAC4 | |
| SCHEMBL24589117 | 0.86 | GLP1R (0.52) | HPGDSMN1; SMN2HTTGLP1R | |
| SCHEMBL23760365 | 0.86 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2HTTHDAC3HDAC4 | |
| SCHEMBL25875243 | 0.86 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2HTTHDAC3HDAC4 | |
| SCHEMBL26032226 | 0.85 | HPGD (0.43) | HPGDSMN1; SMN2HTTGLP1RHDAC3 | |
| SCHEMBL18430819 | 0.82 | SMN1; SMN2 (0.35) | HPGDSMN1; SMN2HTTHDAC3HDAC4 | |
| SCHEMBL24588474 | 0.82 | GLP1R (0.48) | HPGDSMN1; SMN2HTTGLP1R | |
| SCHEMBL2606134 | 0.82 | SMN1; SMN2 (0.36) | HPGDSMN1; SMN2HTTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212182-A1 | ANTI-TUMOR COMPOUND AND PREPARATION METHOD AND USE THEREOF | DUALITY BIOLOGICS (SUZHOU) CO., LTD. (CN) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212182-A1 | ANTI-TUMOR COMPOUND AND PREPARATION METHOD AND USE THEREOF | RCC2, REN, VHL | HPGD 2980/4885SMN1; SMN2 2081/4885HTT 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.