Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 18/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606671 | 0.89 | AGTR1 (0.41) | AGTR1AGTR2PPARG | |
| SCHEMBL2126672 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL13814622 | 0.81 | TLR7 (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL2126682 | 0.78 | AGTR1 (0.45) | AGTR1AGTR2PPARG | |
| SCHEMBL2125878 | 0.75 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL7891164 | 0.74 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL2126957 | 0.73 | TLR7 (0.44) | AGTR1AGTR2PPARG | |
| SCHEMBL13814579 | 0.69 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL4880144 | 0.69 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL4887978 | 0.67 | AGTR1 (0.60) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076288-A1 | DUAL-ACTING BENZOIMIDAZOLE DERIVATIVE AND THEIR USE AS ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2009-06-18 | — | — | WO | disclosed |