Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.79 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
| ▸ | F11 | P03951 | 1/20 | 0.64 |
| ▸ | ELANE | P08246 | 7/20 | 0.59 |
| ▸ | HTRA1 | Q92743 | 3/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066721 | 1.00 | KLK7 (0.79) | KLK7PLGF11ELANEHTRA1 | |
| SCHEMBL13815042 | 0.95 | KLK7 (0.72) | KLK7PLGF11ELANEHTRA1 | |
| SCHEMBL13823022 | 0.95 | KLK7 (0.77) | KLK7PLGF11ELANEHTRA1 | |
| SCHEMBL11961105 | 0.90 | KLK7 (0.67) | KLK7PLGF11ELANEHTRA1 | |
| SCHEMBL6754840 | 0.90 | KLK7 (0.70) | KLK7PLGF11ELANEHTRA1 | |
| SCHEMBL18698808 | 0.88 | KLK7 (1.00) | KLK7PLGF11ELANEF2 | |
| SCHEMBL18698806 | 0.88 | KLK7 (1.00) | KLK7PLGF11ELANEF2 | |
| SCHEMBL13554878 | 0.88 | KLK7 (1.00) | KLK7PLGF11ELANEF2 | |
| SCHEMBL19336662 | 0.88 | KLK7 (1.00) | KLK7PLGF11ELANEF2 | |
| SCHEMBL15524570 | 0.88 | KLK7 (1.00) | KLK7PLGF11ELANEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127044-B2 | Cyclic depsipeptides | NOVARTIS AG (CH) | 2015-09-08 | — | — | US | disclosed |
| US-20090156472-A1 | Cyclic Depsipeptides | NOVARTIS AG (CH) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156472-A1 | Cyclic Depsipeptides | SERPINB1, ELANE, KLK7 | KLK7 3/4885PLG 48/4885F11 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.