Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13815082 | 0.93 | AAK1 (0.44) | AAK1POLBCHEK1NPY4RNPY1R | |
| SCHEMBL19445664 | 0.89 | NPY4R (0.41) | AAK1NPY4RNPY1R | |
| SCHEMBL19445851 | 0.87 | NPC1 (0.39) | AAK1POLBLMNA | |
| SCHEMBL10262675 | 0.85 | NPY4R (0.42) | AAK1NPY4RNPY1RLMNA | |
| SCHEMBL16285905 | 0.85 | NPY4R (0.42) | AAK1NPY4RNPY1RLMNA | |
| SCHEMBL12444369 | 0.85 | NPY4R (0.42) | AAK1NPY4RNPY1RLMNA | |
| SCHEMBL10261740 | 0.85 | NPY4R (0.44) | AAK1NPY4RNPY1R | |
| SCHEMBL15277771 | 0.85 | NPY4R (0.42) | AAK1NPY4RNPY1R | |
| SCHEMBL15138938 | 0.85 | NPY4R (0.42) | AAK1NPY4RNPY1RLMNA | |
| SCHEMBL13815091 | 0.85 | AAK1 (0.48) | AAK1CHEK1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553876-B2 | Polycationic compounds and uses thereof | POLYMEDIX, INC. (US) | 2009-06-30 | — | — | US | disclosed |