Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.48 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319568 | 0.96 | SUV39H2 (0.51) | AAK1SUV39H2LTA4HCHEK1TERT | |
| SCHEMBL13815099 | 0.91 | AAK1 (0.48) | AAK1SUV39H2LTA4HCHEK1TERT | |
| SCHEMBL13815084 | 0.87 | SUV39H2 (0.51) | AAK1SUV39H2LTA4HCHEK1TERT | |
| SCHEMBL13815093 | 0.85 | AAK1 (0.43) | AAK1CHEK1ROCK2ROCK1 | |
| SCHEMBL10261894 | 0.82 | ERAP2 (0.43) | AAK1SUV39H2LTA4H | |
| SCHEMBL10262460 | 0.82 | ERAP2 (0.43) | AAK1SUV39H2LTA4H | |
| SCHEMBL15317940 | 0.81 | ERAP2 (0.48) | AAK1SUV39H2LTA4HTERT | |
| SCHEMBL19945112 | 0.81 | ERAP2 (0.46) | AAK1SUV39H2LTA4HTERT | |
| SCHEMBL21371608 | 0.81 | ERAP2 (0.46) | AAK1SUV39H2LTA4HTERT | |
| SCHEMBL19445796 | 0.81 | ERAP2 (0.46) | AAK1SUV39H2LTA4HTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553876-B2 | Polycationic compounds and uses thereof | POLYMEDIX, INC. (US) | 2009-06-30 | — | — | US | disclosed |