SCHEMBL138151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17188542	0.81	ESR1 (0.48)	TSHRTDP1KDM4EALDH1A1CYP3A4
	SCHEMBL135668	0.80	MAPK1 (0.56)	CYP2A6TDP1MAPTMAPK1ALDH1A1
	SCHEMBL10245982	0.78	ALDH1A1 (0.42)	TSHRTDP1MAPTCA2SMN1; SMN2
	SCHEMBL10245980	0.78	ALDH1A1 (0.42)	TSHRCYP2A6TDP1MAPK1ALDH1A1
	SCHEMBL202261	0.78	MAPK1 (0.43)	TDP1NPC1MAPTMAPK1KDM4E
	SCHEMBL1456487	0.77	TDP1 (0.42)	TDP1NPC1RAB9AMAPTMAPK1
	SCHEMBL6776986	0.76	MEN1 (0.41)	TSHRCYP2A6TDP1ACHEMAPK1
	SCHEMBL4670014	0.76	TSHR (0.40)	TSHRCYP2A6TDP1NPC1RAB9A
	SCHEMBL25689797	0.75	EPHX2 (0.44)	TDP1MAPTKDM4EGAAKMT2A
	SCHEMBL11152162	0.74	MAPK1 (0.59)	TSHRCYP2A6TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.