Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.35 |
| ▸ | GPR6 | P46095 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991542 | 0.94 | PRKCQ (0.38) | PRKCQPRKCDLRRK2PTK2GPR6 | |
| SCHEMBL11991544 | 0.87 | PTK2 (0.37) | PRKCQPRKCDLRRK2PTK2BRAF | |
| SCHEMBL13947015 | 0.87 | PTK2 (0.38) | LRRK2PTK2IRAK4BRAFKDR | |
| SCHEMBL11922630 | 0.82 | SCN9A (0.33) | LRRK2PTK2IRAK4DHODH | |
| SCHEMBL11922636 | 0.82 | PTK2 (0.39) | LRRK2PTK2GPR6IRAK4 | |
| SCHEMBL11991485 | 0.80 | — | — | |
| SCHEMBL11991547 | 0.78 | PTGER1 (0.30) | — | |
| SCHEMBL13044755 | 0.78 | CFTR (0.46) | PTK2PIK3CA | |
| SCHEMBL11922595 | 0.77 | PTK2 (0.34) | LRRK2PTK2IRAK4PIK3CA | |
| SCHEMBL13815822 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076747-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |