Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991544 | 0.94 | PTK2 (0.37) | PTK2LRRK2BRAFKDRCFTR | |
| SCHEMBL11991542 | 0.93 | PRKCQ (0.38) | PTK2LRRK2BRAFKDRCFTR | |
| SCHEMBL11922636 | 0.90 | PTK2 (0.39) | PTK2LRRK2IRAK4 | |
| SCHEMBL11922595 | 0.87 | PTK2 (0.34) | PTK2LRRK2CFTRIRAK4RIPK1 | |
| SCHEMBL13815740 | 0.87 | PRKCQ (0.38) | PTK2LRRK2BRAFKDRIRAK4 | |
| SCHEMBL13044750 | 0.85 | PTK2 (0.35) | PTK2LRRK2CFTRHCRTR1HCRTR2 | |
| SCHEMBL13044755 | 0.85 | CFTR (0.46) | PTK2CFTRRIPK1KDM4EALDH1A1 | |
| SCHEMBL11991450 | 0.84 | PTK2 (0.36) | PTK2LRRK2CFTRRIPK1 | |
| SCHEMBL11991528 | 0.83 | PTK2 (0.33) | PTK2LRRK2CFTRRIPK1 | |
| SCHEMBL11991478 | 0.82 | PTK2 (0.32) | PTK2LRRK2CFTRRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018656-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |