SCHEMBL138162

SCHEMBL138162

NC(=O)COc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.68
KDM4E B2RXH2 2/20 0.58
HTT P42858 1/20 0.58
TP53 P04637 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
PARP10 Q53GL7 1/20 0.55
HPGD P15428 2/20 0.54
ALDH1A1 P00352 2/20 0.54
ALPL P05186 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
CYP19A1 P11511 2/20 0.53
ACACA Q13085 1/20 0.51
FFAR1 O14842 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1291208 0.98 ALOX15 (0.65) ALOX15KDM4EHTTTP53MAPT
Hydrochloric Acid SCHEMBL27524256 0.98 ALOX15 (0.65) ALOX15KDM4EHTTTP53MAPT
SCHEMBL29145072 0.98 ALOX15 (0.65) ALOX15KDM4EHTTTP53MAPT
SCHEMBL8358087 0.92 ALOX15 (0.59) ALOX15KDM4EHTTTP53MAPT
Ethylamine SCHEMBL27389141 0.92 ALOX15 (0.59) ALOX15KDM4EHTTTP53MAPT
SCHEMBL1812614 0.92 SMN1; SMN2 (0.65) ALOX15KDM4EHTTTP53MAPT
Phenol SCHEMBL27278869 0.92 ALOX15 (0.59) ALOX15KDM4EHTTTP53MAPT
Diamidophosphate SCHEMBL30995890 0.89 ALOX15 (0.55) ALOX15KDM4EHTTTP53MAPT
Trifluoroacetic Acid SCHEMBL6382769 0.89 ALOX15 (0.55) ALOX15KDM4EHTTTP53MAPT
SCHEMBL10506137 0.88 MEN1 (0.58) ALOX15KDM4EHTTTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4174 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702096-A Method for recycling battery negative electrode graphite, regenerated graphite material prepared by method and application of regenerated graphite material 广东邦普循环科技有限公司 2024-09-27 CN claimed
US-20240218051-A1 MODIFIED BINDING POLYPEPTIDES FOR OPTIMIZED DRUG CONJUGATION GENZYME CORPORATION 2024-07-04 US claimed
CN-118127115-A Method for preparing phenoxyacetamido penicillin potassium salt through two-step catalysis 内蒙古常盛制药有限公司 2024-06-04 CN claimed
CN-117946031-A Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors 北京大学 2024-04-30 CN claimed
US-11879004-B2 Modified binding polypeptides for optimized drug conjugation GENZYME CORPORATION (US) 2024-01-23 US claimed
US-20230391849-A1 MODIFIED BINDING POLYPEPTIDES FOR OPTIMIZED DRUG CONJUGATION GENZYME CORPORATION 2023-12-07 US claimed
CN-117106844-A Method for synthesizing phenoxyacetamido penicillin potassium salt by fermentation method 内蒙古常盛制药有限公司 2023-11-24 CN claimed
CN-117069679-A N- (substituted phenyl) thiazole phenoxyacetamide compound and preparation method and application thereof 湖南省农业生物技术研究所 2023-11-17 CN claimed
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2023-10-05 US claimed
CN-116589482-A Metal beta-lactamase fluorescent probe and preparation method and application thereof 南京工业大学 2023-08-15 CN claimed
US-4046757-A 2-Optionally substituted alkyl-and phenylsulfonylphenyl-azo-phenyl dyes and a process for their synthesis SANDOZ LTD. (CH) 1977-09-06 US claimed
US-4042585-A Process for preparation of 3-halomethylcephems ELI LILLY AND COMPANY (US) 1977-08-16 US claimed
US-4038275-A PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS ELI LILLY AND COMPANY (US) 1977-07-26 US claimed
US-4031084-A Process for cephalosporin antibiotic intermediates ELI LILLY AND COMPANY (US) 1977-06-21 US claimed
US-4022773-A 7-ACYLAMINO-3-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACIDS, 1-OXIDES ISHIMARU TOSHIYASU 1977-05-10 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3989685-A FROM PENICILLIN-1-OXIDE SHINOGI & CO., LTD. (JA) 1976-11-02 US claimed
US-3978039-A POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-24 US claimed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US claimed
US-3951951-A Azetidinones BEECHAM GROUP LIMITED (EN) 1976-04-20 US claimed