Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028780 | 1.00 | KCNH2 (0.76) | KCNH2KIF11 | |
| SCHEMBL1381684 | 1.00 | KCNH2 (0.76) | KCNH2KIF11 | |
| SCHEMBL1929825 | 1.00 | KCNH2 (0.76) | KCNH2KIF11 | |
| SCHEMBL1929829 | 1.00 | KCNH2 (0.76) | KCNH2KIF11 | |
| SCHEMBL6529273 | 1.00 | KCNH2 (0.76) | KCNH2KIF11 | |
| SCHEMBL4057149 | 0.88 | KCNH2 (0.89) | KCNH2KIF11 | |
| SCHEMBL13655871 | 0.88 | KCNH2 (0.89) | KCNH2KIF11 | |
| SCHEMBL4062744 | 0.88 | KCNH2 (0.89) | KCNH2KIF11 | |
| SCHEMBL4058089 | 0.86 | KCNH2 (1.00) | KCNH2KIF11 | |
| SCHEMBL4058145 | 0.82 | KIF11 (1.00) | KCNH2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4773961-B2 | — | — | 2011-09-14 | — | — | JP | claimed |
| JP-2007502774-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1664026-A1 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005019206-A1 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2005-03-03 | — | — | WO | claimed |
| EP-1664026-A1 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005019206-A1 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2005-03-03 | — | — | WO | disclosed |