Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | ACACA | Q13085 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817871 | 0.86 | ACACB (0.47) | TSHRPOLBEPHX1ACACBACACA | |
| SCHEMBL13817862 | 0.70 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL2355632 | 0.69 | ACACB (0.59) | ACACBACACAHSD17B10 | |
| SCHEMBL13761083 | 0.68 | HRH3 (0.43) | TSHRPOLBRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10079442 | 0.68 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL13342935 | 0.67 | POLB (0.60) | TSHRPOLBEPHX1RAB9ASMN1; SMN2 | |
| SCHEMBL2355638 | 0.66 | ACACB (0.50) | ACACBACACASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL2348656 | 0.66 | ACACB (0.72) | ACACBACACA | |
| SCHEMBL13745331 | 0.66 | ACACB (0.52) | ACACBACACAKMT2A | |
| SCHEMBL13342919 | 0.65 | RAB9A (0.62) | TSHRPOLBEPHX1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547660-B2 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | BAYER AKTIENGESELLSCHAFT (DE) | 2009-06-16 | — | — | US | disclosed |
| US-7547660-B2 | Phenyl-substituted 4-hydroxy-tetrahydropyridones | BAYER AKTIENGESELLSCHAFT (DE) | 2009-06-16 | — | — | US | disclosed |
| EP-1276741-B1 | PHENYL SUBSTITUTED 4-HYDROXY TETRAHYDROPYRIDONE AND ITS USE AS PESTICIDE AND HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2008-12-31 | — | — | EP | disclosed |