Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 8/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 16/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818646 | 0.81 | EGLN3 (0.39) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL3562671 | 0.81 | EGLN3 (0.41) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL13818645 | 0.78 | EGLN3 (0.38) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL13818925 | 0.76 | EGLN3 (0.38) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL3520599 | 0.72 | FTO (0.48) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL3524375 | 0.69 | EGLN3 (0.57) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL3525356 | 0.68 | EGLN3 (0.43) | EGLN3EGLN1EGLN2FTO | |
| SCHEMBL3530712 | 0.68 | EGLN3 (0.42) | EGLN3EGLN1EGLN2FTO | |
| SCHEMBL3517879 | 0.67 | EGLN3 (0.48) | EGLN3EGLN1EGLN2FTOFLT1 | |
| SCHEMBL3522552 | 0.67 | EGLN3 (0.46) | EGLN3EGLN1EGLN2FTOFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073497-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |