Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 7/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819276 | 0.87 | MMP1 (0.50) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL4341914 | 0.82 | MMP1 (0.42) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819355 | 0.81 | MMP1 (0.52) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819277 | 0.81 | MMP1 (0.55) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819719 | 0.80 | MMP1 (0.53) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819469 | 0.80 | MMP1 (0.53) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819470 | 0.80 | MMP1 (0.52) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819278 | 0.80 | MMP1 (0.52) | PARP15MMP1MMP2MMP3MMP9 | |
| SCHEMBL13819280 | 0.79 | MMP1 (0.52) | MMP1MMP2MMP3MMP9MMP12 | |
| SCHEMBL13819362 | 0.79 | MMP1 (0.55) | MMP1MMP2MMP3MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |