SCHEMBL13819331

SCHEMBL13819331

CC(C)(C)P1(=O)CO[C@H](Cn2ccc(N)nc2=O)CO1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.70
HPRT1 P00492 2/20 0.33
LMNA P02545 3/20 0.32
CACNA1F O60840 2/20 0.32
ALB P02768 2/20 0.32
MAPT P10636 2/20 0.32
CACNA1D Q01668 2/20 0.32
CACNA1S Q13698 2/20 0.32
CACNA1C Q13936 2/20 0.32
PDE3A Q14432 2/20 0.32
SLC22A6 Q4U2R8 1/20 0.31
THRB P10828 1/20 0.31
MTOR P42345 1/20 0.31
MDM2 Q00987 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10047653 0.85 FGFR1 (0.74) FGFR1HPRT1LMNACACNA1FALB
SCHEMBL13825656 0.83 FGFR1 (0.75) FGFR1HPRT1LMNACACNA1FALB
Cyclic Cidofovir SCHEMBL140858 0.82 FGFR1 (1.00) FGFR1HPRT1LMNACACNA1FALB
Cyclic Cidofovir SCHEMBL2380283 0.82 FGFR1 (1.00) FGFR1HPRT1LMNACACNA1FALB
Cyclic Cidofovir SCHEMBL14461986 0.82 FGFR1 (1.00) FGFR1HPRT1LMNACACNA1FALB
SCHEMBL14308878 0.82 FGFR1 (0.71) FGFR1HPRT1LMNACACNA1FALB
SCHEMBL10047660 0.81 FGFR1 (0.69) FGFR1HPRT1LMNACACNA1FALB
SCHEMBL27292735 0.80 FGFR1 (0.69) FGFR1LMNACACNA1FALBMAPT
SCHEMBL14044325 0.78 FGFR1 (0.68) FGFR1HPRT1SLC22A6
SCHEMBL26803955 0.77 FGFR1 (0.65) FGFR1HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8309565-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-13 US disclosed