Cyclic Cidofovir

Cyclic Cidofovir

SCHEMBL140858

Nc1ccn(C[C@H]2COP(=O)(O)CO2)c(=O)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 1.00
HPRT1 P00492 2/20 0.48
LMNA P02545 3/20 0.36
PDE3A Q14432 3/20 0.36
CACNA1F O60840 2/20 0.36
ALB P02768 2/20 0.36
MAPT P10636 2/20 0.36
CACNA1D Q01668 2/20 0.36
CACNA1S Q13698 2/20 0.36
CACNA1C Q13936 2/20 0.36
POLB P06746 1/20 0.35
THRB P10828 1/20 0.34
MTOR P42345 1/20 0.34
MDM2 Q00987 1/20 0.34
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
POLG P54098 2/20 0.33
PDE4D Q08499 1/20 0.33
SLC29A1 Q99808 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclic Cidofovir SCHEMBL14461986 1.00 FGFR1 (1.00) FGFR1HPRT1LMNAPDE3ACACNA1F
Cyclic Cidofovir SCHEMBL2380283 1.00 FGFR1 (1.00) FGFR1HPRT1LMNAPDE3ACACNA1F
SCHEMBL13825656 0.86 FGFR1 (0.75) FGFR1HPRT1LMNAPDE3ACACNA1F
SCHEMBL10047653 0.85 FGFR1 (0.74) FGFR1HPRT1LMNAPDE3ACACNA1F
SCHEMBL13799135 0.85 FGFR1 (0.74) FGFR1HPRT1
SCHEMBL13799138 0.85 FGFR1 (0.74) FGFR1HPRT1
SCHEMBL27292735 0.83 FGFR1 (0.69) FGFR1LMNAPDE3ACACNA1FALB
SCHEMBL14308878 0.82 FGFR1 (0.71) FGFR1HPRT1LMNAPDE3ACACNA1F
SCHEMBL13819331 0.82 FGFR1 (0.70) FGFR1HPRT1LMNAPDE3ACACNA1F
SCHEMBL10047660 0.82 FGFR1 (0.69) FGFR1HPRT1LMNAPDE3ACACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205257-A1 CYCLIC CIDOFOVIR OR A PRODRUG THEREOF FOR USE IN THE TREATMENT OR PREVENTION OF AFRICAN SWINE FEVER VIROVET NV (BE) 2025-06-26 US claimed
EP-3147611-B1 METHOD AND SYSTEM FOR SEPARATING CARBON DIOXIDE FROM FLUE GAS GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2024-07-17 EP claimed
CN-115314609-B Automatic acquisition method and device for fire hole video of aluminum electrolysis cell 中南大学 2023-11-28 CN claimed
CN-115314609-A Automatic acquisition method and device for aluminum electrolysis cell fire hole video 中南大学 2022-11-08 CN claimed
EP-3384907-B1 ORAL VETERINARY COMPOSITION WITH GABAPENTIN CHAIT AUERBACH JAIME SAMUEL (MX) 2026-03-25 EP disclosed
US-20260073869-A1 DISPLAY DEVICE JAPAN DISPLAY INC (JP) 2026-03-12 US disclosed
US-12397058-B2 Metabolically stable prodrugs TSRL, INC. (US) 2025-08-26 US disclosed
US-20250205257-A1 CYCLIC CIDOFOVIR OR A PRODRUG THEREOF FOR USE IN THE TREATMENT OR PREVENTION OF AFRICAN SWINE FEVER VIROVET NV (BE) 2025-06-26 US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
WO-2024259930-A9 PHOSPHONATE COMPOUND AND MEDICAL USE THEREOF 润佳(苏州)医药科技有限公司 2025-04-24 WO disclosed
US-12283236-B2 Processor for compensate image and operation method thereof NOVATEK MICROELECTRONICS CORP. (TW) 2025-04-22 US disclosed
CN-119854361-A Internet of things block chain slicing method and device 北京邮电大学 2025-04-18 CN disclosed
WO-2007130783-A2 METABOLICALLY STABLE ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES CHIMERIX, INC. (US) 2007-11-15 WO disclosed
EP-0874858-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1998-11-04 EP disclosed
US-5756486-A CYCLIZED NUCLEOTIDE; VIRICIDE GILEAD SCIENCES, INC. (US) 1998-05-26 US disclosed
US-5717095-A PHOSPHONATES CYTOSINE COMPOUND GILEAD SCIENCES, INC. (US) 1998-02-10 US disclosed
WO-1997024361-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1997-07-10 WO disclosed
US-5591851-A ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 1997-01-07 US disclosed
EP-0719274-A1 METHOD FOR DOSING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 1996-07-03 EP disclosed
WO-1995007919-A1 METHOD FOR DOSING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 1995-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250205257-A1 CYCLIC CIDOFOVIR OR A PRODRUG THEREOF FOR USE IN THE TREATMENT OR PREVENTION OF AFRICAN SWINE FEVER ATIC, PIGS, TYMP FGFR1 1493/4885HPRT1 478/4885LMNA 1007/4885
US-20260073869-A1 DISPLAY DEVICE NECTIN4, EPHA4, L1CAM FGFR1 2616/4885HPRT1 3474/4885LMNA 3271/4885
US-12397058-B2 Metabolically stable prodrugs CES1, CES2, CYP2S1 FGFR1 1170/4885HPRT1 387/4885LMNA 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.