Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 12/20 | 0.59 |
| ▸ | PPARG | P37231 | 11/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819764 | 0.90 | MAOB (0.57) | MRGPRX4PPARAPPARGPPARDNR4A2 | |
| SCHEMBL13819766 | 0.90 | PPARA (0.58) | MRGPRX4PPARAPPARGPPARDNR4A2 | |
| SCHEMBL13819762 | 0.88 | NR4A2 (0.60) | MRGPRX4PPARAPPARGPPARDNR4A2 | |
| SCHEMBL4338925 | 0.88 | PPARG (0.55) | MRGPRX4PPARAPPARGPPARD | |
| SCHEMBL4346891 | 0.85 | PPARG (0.51) | MRGPRX4PPARAPPARGPPARD | |
| SCHEMBL13819711 | 0.85 | PPARG (0.57) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL13810005 | 0.83 | PPARA (0.49) | MRGPRX4PPARAPPARGPPARD | |
| SCHEMBL4335055 | 0.83 | SMN1; SMN2 (0.52) | PPARAPPARGPPARDMAPTHTT | |
| SCHEMBL4328261 | 0.82 | MGLL (0.53) | PPARAPPARGPPARDL3MBTL1 | |
| SCHEMBL13819487 | 0.81 | PPARG (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |