Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 1/20 | 0.51 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 16/20 | 0.50 |
| ▸ | PPARG | P37231 | 14/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819721 | 0.85 | PPARG (0.55) | SHMT1SHMT2PPARAPPARGPPARD | |
| SCHEMBL6650974 | 0.82 | PPARA (0.45) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL13819476 | 0.82 | PPARG (0.52) | PPARAPPARGPPARD | |
| SCHEMBL6720420 | 0.81 | PPARA (0.44) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL6653525 | 0.81 | PPARA (0.44) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL13819716 | 0.80 | MRGPRX4 (0.59) | PPARAPPARG | |
| SCHEMBL13819776 | 0.80 | MRGPRX4 (0.59) | PPARAPPARG | |
| SCHEMBL13819768 | 0.79 | PPARA (0.47) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL13819821 | 0.78 | NR4A2 (0.57) | PPARAPPARGPPARD | |
| SCHEMBL13819373 | 0.78 | NR4A2 (0.57) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |