Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.52 |
| ▸ | PPARA | Q07869 | 13/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819721 | 0.89 | PPARG (0.55) | PPARGPPARAPTGS2PPARD | |
| SCHEMBL13819720 | 0.85 | PPARG (0.57) | PPARGPPARAPTGS2PPARD | |
| SCHEMBL13819283 | 0.82 | PPARG (0.47) | PPARGPPARAPTGS2PPARD | |
| SCHEMBL13819481 | 0.82 | SHMT1 (0.51) | PPARGPPARAPPARD | |
| SCHEMBL4327422 | 0.82 | PPARA (0.49) | PPARGPPARAPPARD | |
| SCHEMBL13819474 | 0.80 | FFAR1 (0.52) | PPARGPPARAPPARD | |
| SCHEMBL13819375 | 0.80 | PPARA (0.47) | PPARGPPARAPPARDFPR2 | |
| SCHEMBL13819376 | 0.79 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL6651835 | 0.78 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL4336962 | 0.78 | PPARG (0.54) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |