Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.57 |
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819721 | 0.88 | PPARG (0.55) | PPARGPPARAPPARDPTGS2 | |
| SCHEMBL13819476 | 0.85 | PPARG (0.52) | PPARGPPARAPPARDPTGS2 | |
| SCHEMBL13819283 | 0.84 | PPARG (0.47) | PPARGPPARAPPARDPTGS2 | |
| SCHEMBL4342524 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDFFAR1SRR | |
| SCHEMBL13819376 | 0.81 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL13819357 | 0.80 | MAOB (0.53) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL13819711 | 0.80 | PPARG (0.57) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL2866290 | 0.79 | GRIA2 (0.48) | PPARGPPARAPPARDSRR | |
| SCHEMBL4348224 | 0.79 | GRIA2 (0.48) | PPARGPPARAPPARDSRR | |
| SCHEMBL13819285 | 0.78 | PPARG (0.46) | PPARGPPARAPPARDSRRPSAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |