Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.64 |
| ▸ | CTSL | P07711 | 9/20 | 0.64 |
| ▸ | CTSS | P25774 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241308 | 0.86 | CTSK (0.74) | CTSKCTSLCTSS | |
| SCHEMBL11925976 | 0.86 | CTSK (0.74) | CTSKCTSLCTSS | |
| SCHEMBL21137665 | 0.86 | CTSK (0.74) | CTSKCTSLCTSS | |
| SCHEMBL13826893 | 0.78 | CTSK (0.61) | CTSKCTSLCTSS | |
| SCHEMBL11925968 | 0.78 | CTSK (1.00) | CTSKCTSLCTSS | |
| SCHEMBL14878498 | 0.78 | CTSK (0.60) | CTSKCTSLCTSSSMN1; SMN2 | |
| SCHEMBL21137261 | 0.78 | CTSK (1.00) | CTSKCTSLCTSS | |
| SCHEMBL15241306 | 0.78 | CTSK (1.00) | CTSKCTSLCTSS | |
| SCHEMBL15241298 | 0.78 | CTSK (1.00) | CTSKCTSLCTSS | |
| SCHEMBL22266814 | 0.76 | CTSK (0.67) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426421-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2013-04-23 | — | — | US | disclosed |
| US-8426421-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2013-04-23 | — | — | US | disclosed |
| US-20120289519-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2012-11-15 | — | — | US | disclosed |
| US-20120289519-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289519-A1 | PROTEASE INHIBITORS | F2RL1, F2RL3, PREP | CTSK 67/4885CTSL 7/4885CTSS 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.