Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012051 | 0.93 | ADRB2 (0.43) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL12730196 | 0.91 | BRD4 (0.40) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL12012046 | 0.90 | BRD4 (0.44) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL14404729 | 0.86 | ADRB2 (0.45) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL16671983 | 0.85 | ADRB2 (0.53) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL15354527 | 0.84 | BRD4 (0.35) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL13165210 | 0.84 | PTPN1 (0.39) | BRD4ADRB2HTR1APARP1HRH3 | |
| SCHEMBL16984444 | 0.83 | ADRB2 (0.43) | BRD4ADRB2HTR1AABL1PARP1 | |
| SCHEMBL1105644 | 0.83 | PTPN1 (0.39) | BRD4ADRB2HTR1AABL1HRH3 | |
| SCHEMBL17322726 | 0.82 | ADRB2 (0.51) | BRD4ADRB2HTR1AABL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9423323-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-9018396-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2015-04-28 | — | — | US | disclosed |
| US-8569506-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120288871-A1 | Modified Carbocyanine Dyes and Their Conjugates | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288871-A1 | Modified Carbocyanine Dyes and Their Conjugates | IK, CBR3, DRD5 | BRD4 217/4885ADRB2 2725/4885HTR1A 604/4885 |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | BRD4 217/4885ADRB2 2725/4885HTR1A 604/4885 |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | BRD4 217/4885ADRB2 2725/4885HTR1A 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.