Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380890 | 0.94 | KCNH2 (0.42) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL1380188 | 0.92 | KCNH2 (0.39) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL1382150 | 0.89 | KCNH2 (0.39) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL1385935 | 0.88 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL1380701 | 0.87 | KCNH2 (0.41) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4511593 | 0.86 | KCNH2 (0.40) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL4511909 | 0.85 | KCNH2 (0.36) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL6501104 | 0.85 | KCNH2 (0.39) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL4519134 | 0.85 | KCNH2 (0.42) | KCNH2POLBKDM4EPRKD3ALDH1A1 | |
| SCHEMBL1383542 | 0.85 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4811978-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | claimed |