Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.31 |
| ▸ | LITAF | Q99732 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517410 | 0.93 | KCNH2 (0.39) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL1381764 | 0.89 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL7512498 | 0.88 | KCNH2 (0.37) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL1382555 | 0.86 | TOP1 (0.30) | — | |
| SCHEMBL1386477 | 0.85 | KCNH2 (0.35) | KCNH2TNFLITAF | |
| SCHEMBL1382071 | 0.85 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL4517554 | 0.84 | KCNH2 (0.39) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL4525946 | 0.84 | KCNH2 (0.33) | KCNH2TNFLITAFCYP3A4 | |
| SCHEMBL4525375 | 0.80 | TOP1 (0.31) | KCNH2CYP3A4 | |
| SCHEMBL4718338 | 0.79 | KCNH2 (0.33) | KCNH2TNFLITAFCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4811978-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | claimed |