Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.67 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368040 | 0.82 | PARP1 (0.55) | PARP1HRH3 | |
| SCHEMBL30102646 | 0.80 | SMYD3 (0.68) | PARP1SMYD3CHRNA7TNKSSMN1; SMN2 | |
| SCHEMBL602081 | 0.80 | SMYD3 (0.58) | SMYD3CHRNA7TNKSCYP3A4ALDH1A1 | |
| SCHEMBL3369864 | 0.80 | PARP1 (0.80) | PARP1 | |
| SCHEMBL21490100 | 0.79 | SMYD3 (0.74) | PARP1SMYD3CHRNA7TNKSSMN1; SMN2 | |
| SCHEMBL19710047 | 0.79 | SMYD3 (0.74) | PARP1SMYD3CHRNA7TNKSSMN1; SMN2 | |
| SCHEMBL1652273 | 0.78 | KDM5A (0.58) | PARP1CHRNA7CYP3A4CYP2D6HTR4 | |
| SCHEMBL21490183 | 0.75 | SMYD3 (1.00) | SMYD3CHRNA7TNKS | |
| SCHEMBL19710384 | 0.75 | SMYD3 (1.00) | SMYD3CHRNA7TNKS | |
| SCHEMBL18389994 | 0.74 | HRH3 (0.67) | CYP3A4CYP2D6HTR4ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4658940-B2 | — | — | 2011-03-23 | — | — | JP | claimed |