Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 11/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2225153 | 0.99 | MAPT (0.52) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2222628 | 0.91 | MAPT (0.54) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2222789 | 0.89 | MAPT (0.52) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL14632680 | 0.86 | MAPT (0.51) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2226372 | 0.83 | MAPT (0.56) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2222287 | 0.83 | MAPT (0.53) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2225327 | 0.83 | MAPT (0.55) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL12516114 | 0.83 | MAPT (0.59) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2222568 | 0.83 | MAPT (0.61) | MAPTKDM4ENPSR1POLBL3MBTL1 | |
| SCHEMBL2224333 | 0.83 | MAPT (0.61) | MAPTKDM4ENPSR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523665-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | Glaxo Group Limited (GB) | 2012-11-21 | — | — | EP | disclosed |