SCHEMBL2222628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14632680	0.94	MAPT (0.51)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL13822342	0.91	MAPT (0.53)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL2221990	0.90	MAPT (0.55)	MAPTKDM4ENPSR1POLBL3MBTL1
	Hydrochloric Acid SCHEMBL2225153	0.90	MAPT (0.52)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL2222896	0.87	MAPT (0.59)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL12516114	0.86	MAPT (0.59)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL2224197	0.85	MAPT (0.62)	MAPTKDM4ENPSR1POLBL3MBTL1
	Hydrochloric Acid SCHEMBL2223700	0.85	MAPT (0.58)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL2222789	0.85	MAPT (0.52)	MAPTKDM4ENPSR1POLBL3MBTL1
	SCHEMBL2221835	0.84	MAPT (0.53)	MAPTKDM4ENPSR1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.