Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648012 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL647956 | 0.93 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL646678 | 0.93 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL645954 | 0.88 | DPP4 (0.78) | DPP4DPP8DPP9 | |
| SCHEMBL648082 | 0.88 | DPP4 (0.87) | DPP4DPP8DPP9 | |
| SCHEMBL1377256 | 0.84 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| SCHEMBL646373 | 0.84 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| SCHEMBL645964 | 0.81 | DPP4 (0.68) | DPP4 | |
| SCHEMBL12398798 | 0.81 | DPP4 (0.68) | DPP4DPP8 | |
| SCHEMBL4705704 | 0.79 | DPP4 (0.89) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4712387-B2 | — | — | 2011-06-29 | — | — | JP | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | claimed |
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |