Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646678 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL648012 | 0.93 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1382238 | 0.93 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1377256 | 0.91 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| SCHEMBL646373 | 0.91 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| SCHEMBL6167534 | 0.81 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| SCHEMBL648082 | 0.80 | DPP4 (0.87) | DPP4DPP8DPP9 | |
| SCHEMBL645954 | 0.80 | DPP4 (0.78) | DPP4DPP8DPP9 | |
| SCHEMBL6255154 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL12398848 | 0.77 | DPP4 (0.63) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637546-B2 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DDP-IV) | ABBVIE INC. (US) | 2014-01-28 | — | — | US | claimed |
| US-8119664-B2 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2012-02-21 | — | — | US | claimed |