Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 3/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699074 | 0.94 | CMA1 (0.45) | FABP4FABP5KDM4ECMA1CTSG | |
| SCHEMBL3699071 | 0.94 | CMA1 (0.45) | FABP4FABP5KDM4ECMA1CTSG | |
| SCHEMBL3689406 | 0.86 | PGR (0.38) | THRBTNFCNR2RXFP1 | |
| SCHEMBL3686182 | 0.83 | CMA1 (0.38) | CMA1CTSG | |
| SCHEMBL3687513 | 0.82 | CMA1 (0.38) | KDM4ECMA1CTSG | |
| SCHEMBL3701617 | 0.81 | GAA (0.42) | KDM4EHSD17B10CNR2HDAC1SMN1; SMN2 | |
| SCHEMBL3695212 | 0.81 | CMA1 (0.35) | KDM4ECMA1RXFP1ALDH1A1HPGD | |
| SCHEMBL3683080 | 0.81 | CMA1 (0.35) | KDM4ECMA1RXFP1ALDH1A1HPGD | |
| SCHEMBL3683076 | 0.81 | CMA1 (0.35) | KDM4ECMA1RXFP1ALDH1A1HPGD | |
| SCHEMBL3690021 | 0.80 | CMA1 (0.49) | CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188277-B1 | QUINAZOLINEDIONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2012-11-21 | — | — | EP | disclosed |