Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822818 | 0.85 | F10 (0.42) | F10NPC1RAB9AKMT2AGRM5 | |
| SCHEMBL976355 | 0.83 | F10 (0.45) | F10NPC1RAB9AKMT2AF2 | |
| SCHEMBL977701 | 0.82 | NPC1 (0.55) | F10NPC1RAB9AKMT2AGRM5 | |
| SCHEMBL976270 | 0.82 | NPC1 (0.44) | F10NPC1RAB9AKMT2A | |
| SCHEMBL977873 | 0.81 | TSHR (0.44) | F10NPC1RAB9A | |
| SCHEMBL978019 | 0.81 | F10 (0.51) | F10KMT2AF2F9PRSS1 | |
| SCHEMBL975334 | 0.80 | GRM5 (0.55) | F10NPC1RAB9AKMT2AGRM5 | |
| SCHEMBL976630 | 0.80 | LMNA (0.42) | F10F2F9PRSS1PRSS2 | |
| Sulfuric Acid SCHEMBL977462 | 0.79 | F10 (0.49) | F10KMT2AF2F9PRSS1 | |
| SCHEMBL975030 | 0.79 | SMN1; SMN2 (0.47) | F10KMT2AF2F9PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197552-B1 | NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2012-11-21 | — | — | EP | claimed |