Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 8/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840726 | 0.91 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL7222108 | 0.91 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL7222104 | 0.91 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL8755221 | 0.91 | DNMT1 (0.56) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL21585071 | 0.90 | DNMT1 (0.52) | DNMT1ADRB1DNMT3BTK1 | |
| SCHEMBL3933963 | 0.90 | DNMT1 (0.52) | DNMT1ADRB1DNMT3BTK1 | |
| SCHEMBL3933968 | 0.90 | DNMT1 (0.52) | DNMT1ADRB1DNMT3BTK1 | |
| SCHEMBL23015792 | 0.89 | DNMT1 (0.51) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL20524273 | 0.89 | DNMT1 (0.51) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 | |
| SCHEMBL21626981 | 0.89 | DNMT1 (0.51) | DNMT1ADRB1DNMT3BLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553643-B2 | Method for amplifying target nucleic acid sequences using a primer comprising an AP endonuclease-cleavable linker | EPOCH BIOSCIENCES, INC. (US) | 2009-06-30 | — | — | US | disclosed |